Are you seeing the utilization spike for a brief period of time then return to normal? We are running into the same problem but do not yet have a handle on the cause. For us no backups, snapshots or thin provisioned VMs on the datastores. Only pattern we are seeing is the two problem datastores are 2TB with very large VMs residing on each. VMware support wasn't able to figure it out either. They guessed the HBA driver is sometimes returning bad data to vCenter.
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